Lipid Controls
Medchemexpress LLC DLin-KC2-DMA | 1190197-97-7 | ≥98.0% | 642.09 | 25 MG
DLin-KC2-DMA is an ionizable cationic lipid (pKa≈6) that is virtually non-toxic to antigen presenting cells (APCs). It produces significant siRNA-mediated gene silencing of GAPDH when bound to lipid nanoparticles (LNP). DLin-KC2-DMA can be used in siRNA delivery studies.
- Ionizable cationic lipid (pKa≈6).
- Virtually non-toxic to antigen presenting cells (APCs).
- Produces significant siRNA-mediated gene silencing of GAPDH when bound to lipid nanoparticles (LNP).
- Can be used in siRNA delivery studies.
- High uptake into macrophages and dendritic cells.
- Efficiently promotes release of encapsulated siRNA into the cytosol following uptake via the endocytotic pathway.
- Displays almost no toxicity in primary APCs.
- Effective in silencing target genes in APCs in vivo (5 mg/kg; i.v.; single).
Cayman Chemical DLIn-MC4-DMA 25mg
An ionizable cationic lipid (pKa = 6.93); LNPs containing DLin-MC4-DMA and encapsulating siRNA for F7 reduce its gene expression levels in mice
Cayman Chemical 1 3DIstearoyl2oloyl Glyce 10mg
A triacylglycerol; has been found in Kpangnana, Chinese tallow, and cocoa butters; increases the phagocytic function of reticulo-endothelial cells in mice at 5 and 10 mg per animal
Medchemexpress LLC Dodap | 127512-29-2 | MFCD01321074 | 98.0% | 648.05 g/mol | C41H77NO4 | 5 MG
DODAP is an ionizable cationic lipid used as the lipid component in liposomal formulations for nucleic acid delivery and related research. It is commonly employed to encapsulate siRNA and support intracellular delivery of therapeutic or immunostimulatory agents in vitro and in vivo, with applications in vaccine and inflammation studies.
- Cationic lipid that facilitates siRNA encapsulation and delivery.
- Ionizable with a pKa around 5.59 to aid endosomal release.
- High purity (98.0%) supplied as a liquid for formulation flexibility.
- Available in multiple pack sizes suitable for small-scale experiments.
- Defined storage conditions for long-term stability in pure form and in solvent.
Sigma Aldrich Fine Chemicals Biosciences 1-Palmitoyl-sn-glycero-3-phosphocholine synthetic, >=99% | 17364-16-8 | MFCD00036904 | 25MG
1-Palmitoyl-sn-glycero-3-phosphocholine synthetic, >=99% | Purity: >=99% | Mol Wt: 495.63 | 17364-16-8 | MFCD00036904 | 25MG
Avanti Polar Lipids 1-palmitoyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt), 17618-08-5, MFCD00674362, 25mg
Molecular Formula: C19H38O7PNa, Formula Weight: 432.464, Purity>99%, Storage Temperature: -20°C.
eMolecules 1217306-46-1 | Medchem Express | DLin-K-C3-DMA | 5mg | 705861090 | HY-145225 | 656.137 | C44H81NO2
Medchem Express | Sofosbuvir impurity F | 1mg | 446274409 | HY-I0406 | 1337482-17-3 | 798.695 | C34H45FN4O13P2
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eMolecules Building Block Tool
eMolecules BP Lipid 137 | Broadpharm |654.074 | C40H79NO5 | 96.000 | CCCCCCCCC(CCCCCCCC)OC(=O)CCCCCCN(CCCO)CCCCCC(=O)OCCCCCCC | 50mg | 672542535
BP Lipid 137 | Broadpharm |654.074 | C40H79NO5 | 96.000 | CCCCCCCCC(CCCCCCCC)OC(=O)CCCCCCN(CCCO)CCCCCC(=O)OCCCCCCC | 50mg | 672542535
eMolecules BP Lipid 134 | Broadpharm |696.155 | C43H85NO5 | 0.000 | CCCCCCCCC(CCCCCCCC)OC(=O)CCCCCCCN(CCCO)CCCCCCCC(=O)OCCCCCCC | 50mg | 672542526
BP Lipid 134 | Broadpharm |696.155 | C43H85NO5 | 0.000 | CCCCCCCCC(CCCCCCCC)OC(=O)CCCCCCCN(CCCO)CCCCCCCC(=O)OCCCCCCC | 50mg | 672542526
Medchemexpress LLC DSPE-PEG2000-Mal ammonium | 474922-22-0 | 99.9% | (C2H4O)nC51H92N1O13P.H3N | 50 MG
DSPE-PEG-Maleimide contains DSPE phospholipid and maleimide, used to prepare nanostructured lipid carriers. It extends blood circulation time and provides higher stability for encapsulated agents. Immunoliposomes constructed with DSPE-PEG-Maleimide can be used for the delivery of brain drugs.
- Contains DSPE phospholipid and maleimide
- Prepares nanostructured lipid carriers
- Extends blood circulation time
- Provides higher stability for encapsulated agents
- Immunoliposomes can be used for delivery of brain drugs
Avanti Polar Lipids 3D-PHAD, Powder | 1699735-79-9 | 1 mg
3D-PHAD, Powder | Purity: >99% | Mol Wt: 1537.114 | 1699735-79-9 | 1 mg